Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

Wei Shao, Shu-zhen Zhang, Mi Tang, Xin-hua Zhang, Zheng Zhou, Yan-qing Yin, Qin-bo Zhou, Yuan-yuan Huang, Ying-jun Liu, Eric Wawrousek, Teng Chen, Sheng-bin Li, Ming Xu, Jiang-ning Zhou, Gang Hu and Jia-wei Zhou ()
Additional contact information
Wei Shao: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Shu-zhen Zhang: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Mi Tang: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Xin-hua Zhang: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Zheng Zhou: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Yan-qing Yin: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Qin-bo Zhou: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Yuan-yuan Huang: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Ying-jun Liu: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
Eric Wawrousek: National Eye Institute, NIH
Teng Chen: Xi’an Jiaotong University School of Medicine, Xi’an, Shanxi 710061, China
Sheng-bin Li: Xi’an Jiaotong University School of Medicine, Xi’an, Shanxi 710061, China
Ming Xu: University of Chicago
Jiang-ning Zhou: CAS Key Laboratory of Brain Function and Diseases, School of Life Science, University of Science and Technology of China, Hefei, Anhui 230027, China
Gang Hu: Jiangsu Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, Jiangsu 210029, China
Jia-wei Zhou: Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China

Nature, 2013, vol. 494, issue 7435, 90-94

Abstract: Chronic inflammation is a feature of the ageing brain and some neurodegenerative diseases; the authors show that astrocytes normally suppress neuroinflammation through activation of their DRD2 receptor by CRYAB, potentially opening new avenues for treatments.

Date: 2013
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature11748 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:494:y:2013:i:7435:d:10.1038_nature11748

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature11748

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().