Mitotic cell rounding accelerates epithelial invagination

Takefumi Kondo and Shigeo Hayashi ()
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Takefumi Kondo: Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, 2-2-3, Minatojima-Minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan
Shigeo Hayashi: Laboratory for Morphogenetic Signaling, RIKEN Center for Developmental Biology, 2-2-3, Minatojima-Minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan

Nature, 2013, vol. 494, issue 7435, 125-129

Abstract: Drosophila epithelial tracheal placode invagination is shown to be driven by mitotic cell rounding along with epithelial growth factor receptor signalling and myosin contractility in neighbouring cells, revealing a new cell-division-independent role for mitotic events in morphogenesis.

Date: 2013
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DOI: 10.1038/nature11792

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