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GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas

Scott X. Atwood (), Mischa Li, Alex Lee, Jean Y. Tang and Anthony E. Oro ()
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Scott X. Atwood: Program in Epithelial Biology, Stanford University School of Medicine
Mischa Li: Program in Epithelial Biology, Stanford University School of Medicine
Alex Lee: Program in Epithelial Biology, Stanford University School of Medicine
Jean Y. Tang: Program in Epithelial Biology, Stanford University School of Medicine
Anthony E. Oro: Program in Epithelial Biology, Stanford University School of Medicine

Nature, 2013, vol. 494, issue 7438, 484-488

Abstract: Atypical protein kinase C ι/λ is shown to be critical, through its regulation of the transcription factor GLI, for hedgehog-dependent processes, such as the growth of basal cell carcinomas.

Date: 2013
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DOI: 10.1038/nature11889

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