Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle

Ran Kafri, Jason Levy, Miriam B. Ginzberg, Seungeun Oh, Galit Lahav and Marc W. Kirschner ()
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Ran Kafri: Harvard Medical School
Jason Levy: University of Ottawa
Miriam B. Ginzberg: Harvard Medical School
Seungeun Oh: Harvard Medical School
Galit Lahav: Harvard Medical School
Marc W. Kirschner: Harvard Medical School

Nature, 2013, vol. 494, issue 7438, 480-483

Abstract: A mathematical method, known as ergodic rate analysis, has been developed and used to study the rates of molecular events from single time measurements of large populations of fixed cells; this new method is able to overcome some of the previous limitations with regards to studying cell-size control.

Date: 2013
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DOI: 10.1038/nature11897

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