Rewriting a genome

Emmanuelle Charpentier () and Jennifer A. Doudna ()
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Emmanuelle Charpentier: Emmanuelle Charpentier is at the Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany, in the Laboratory for Molecular Infection Medicine Sweden, Umeå University, Sweden, and at the Hanover Medical School, Hanover, Germany.
Jennifer A. Doudna: Jennifer A. Doudna is at the Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA, Lawrence Berkeley National Laboratory, Berkeley.

Nature, 2013, vol. 495, issue 7439, 50-51

Abstract: A bacterial enzyme that uses guide RNA molecules to target DNA for cleavage has been adopted as a programmable tool to site-specifically modify genomes of cells and organisms, from bacteria and human cells to whole zebrafish.

Date: 2013
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DOI: 10.1038/495050a

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