Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

Lei Ding and Sean J. Morrison ()
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Lei Ding: Howard Hughes Medical Institute, Children’s Research Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
Sean J. Morrison: Howard Hughes Medical Institute, Children’s Research Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA

Nature, 2013, vol. 495, issue 7440, 231-235

Abstract: A study of the physiological sources of the chemokine CXCL12 in mice shows that haematopoietic stem cells occupy a perivascular niche in the bone marrow whereas early lymphoid progenitors occupy a distinct endosteal niche.

Date: 2013
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DOI: 10.1038/nature11885

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