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Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions

Kimberly L. Cooper (), Seungeun Oh, Yongjin Sung, Ramachandra R. Dasari, Marc W. Kirschner and Clifford J. Tabin
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Kimberly L. Cooper: Harvard Medical School
Seungeun Oh: Harvard Medical School
Yongjin Sung: George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology
Ramachandra R. Dasari: George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology
Marc W. Kirschner: Harvard Medical School
Clifford J. Tabin: Harvard Medical School

Nature, 2013, vol. 495, issue 7441, 375-378

Abstract: A microscopy study of the cellular basis of mammalian skeletal elongation in development and evolution reveals three phases of chondrocyte volume enlargement, including a phase of disproportionate fluid increase.

Date: 2013
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DOI: 10.1038/nature11940

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