A central role for TFIID in the pluripotent transcription circuitry

W. W. M. Pim Pijnappel, Daniel Esch, Marijke P. A. Baltissen, Guangming Wu, Nikolai Mischerikow, Atze J. Bergsma, Erik van der Wal, Dong Wook Han, Hermann vom Bruch, Sören Moritz, Phillip Lijnzaad, A. F. Maarten Altelaar, Katrin Sameith, Holm Zaehres, Albert J. R. Heck, Frank C. P. Holstege, Hans R. Schöler and H. T. Marc Timmers ()
Additional contact information
W. W. M. Pim Pijnappel: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
Daniel Esch: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
Marijke P. A. Baltissen: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
Guangming Wu: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
Nikolai Mischerikow: Netherlands Proteomics Center, 3584 CH Utrecht, The Netherlands
Atze J. Bergsma: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
Erik van der Wal: Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands
Dong Wook Han: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
Hermann vom Bruch: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
Sören Moritz: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
Phillip Lijnzaad: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
A. F. Maarten Altelaar: Netherlands Proteomics Center, 3584 CH Utrecht, The Netherlands
Katrin Sameith: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
Holm Zaehres: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
Albert J. R. Heck: Netherlands Proteomics Center, 3584 CH Utrecht, The Netherlands
Frank C. P. Holstege: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands
Hans R. Schöler: Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany
H. T. Marc Timmers: Molecular Cancer Research, University Medical Center Utrecht, 3584 CG Utrecht, The Netherlands

Nature, 2013, vol. 495, issue 7442, 516-519

Abstract: High levels of TFIID, a basal transcription factor, are found to be essential to induce and maintain the transcriptional program of pluripotent cells.

Date: 2013
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DOI: 10.1038/nature11970

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