Sirtuin on a high-fat diet

Poonam Bheda and Cynthia Wolberger ()
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Poonam Bheda: Poonam Bheda is at the Institut Génétique et de Biologie Moleculaire et Cellulaire, Illkirch 67404, France.
Cynthia Wolberger: Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2185, USA.

Nature, 2013, vol. 496, issue 7443, 41-42

Abstract: It emerges that the sirtuin enzyme SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-α. See Letter p.110

Date: 2013
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DOI: 10.1038/496041a

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