Meis1 regulates postnatal cardiomyocyte cell cycle arrest

Ahmed I. Mahmoud, Fatih Kocabas, Shalini A. Muralidhar, Wataru Kimura, Ahmed S. Koura, Suwannee Thet, Enzo R. Porrello and Hesham A. Sadek ()
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Ahmed I. Mahmoud: The University of Texas Southwestern Medical Center
Fatih Kocabas: The University of Texas Southwestern Medical Center
Shalini A. Muralidhar: The University of Texas Southwestern Medical Center
Wataru Kimura: The University of Texas Southwestern Medical Center
Ahmed S. Koura: School of Medicine, Ain Shams University
Suwannee Thet: The University of Texas Southwestern Medical Center
Enzo R. Porrello: School of Biomedical Sciences, The University of Queensland
Hesham A. Sadek: The University of Texas Southwestern Medical Center

Nature, 2013, vol. 497, issue 7448, 249-253

Abstract: The neonatal heart has a high regenerative capacity that is lost in adult life; the transcription factor Meis1 has been identified as a relevant proliferative switch for this transition, providing a potential therapeutic target for adult heart regeneration.

Date: 2013
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DOI: 10.1038/nature12054

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