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Psl trails guide exploration and microcolony formation in Pseudomonas aeruginosa biofilms

Kun Zhao, Boo Shan Tseng, Bernard Beckerman, Fan Jin, Maxsim L. Gibiansky, Joe J. Harrison, Erik Luijten (), Matthew R. Parsek () and Gerard C. L. Wong ()
Additional contact information
Kun Zhao: University of California
Boo Shan Tseng: University of Washington
Bernard Beckerman: Northwestern University
Fan Jin: CAS Key Laboratory of Soft Matter Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China
Maxsim L. Gibiansky: University of California
Joe J. Harrison: University of Washington
Erik Luijten: Northwestern University
Matthew R. Parsek: University of Washington
Gerard C. L. Wong: University of California

Nature, 2013, vol. 497, issue 7449, 388-391

Abstract: Cell-tracking experiments and simulations show that the Psl exopolysaccharide deposited by Pseudomonas aeruginosa guides the surface motility of subsequent cells that encounter the Psl trails, generating a ‘rich-get-richer’ effect that leads to microcolony formation.

Date: 2013
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DOI: 10.1038/nature12155

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