Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics

Gongpu Zhao, Juan R. Perilla, Ernest L. Yufenyuy, Xin Meng, Bo Chen, Jiying Ning, Jinwoo Ahn, Angela M. Gronenborn, Klaus Schulten (), Christopher Aiken () and Peijun Zhang ()
Additional contact information
Gongpu Zhao: University of Pittsburgh School of Medicine
Juan R. Perilla: University of Illinois at Urbana-Champaign
Ernest L. Yufenyuy: Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine
Xin Meng: University of Pittsburgh School of Medicine
Bo Chen: University of Central Florida
Jiying Ning: University of Pittsburgh School of Medicine
Jinwoo Ahn: University of Pittsburgh School of Medicine
Angela M. Gronenborn: University of Pittsburgh School of Medicine
Klaus Schulten: University of Illinois at Urbana-Champaign
Christopher Aiken: Pittsburgh Center for HIV Protein Interactions, University of Pittsburgh School of Medicine
Peijun Zhang: University of Pittsburgh School of Medicine

Nature, 2013, vol. 497, issue 7451, 643-646

Abstract: The structure of the HIV-1 capsid is analysed by cryo-electron microscopy and cryo-electron tomography, allowing presentation of an all-atom molecular dynamics model of the entire capsid.

Date: 2013
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DOI: 10.1038/nature12162

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