Drug for an 'undruggable' protein

Nicole M. Baker and Channing J. Der ()
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Nicole M. Baker: Nicole M. Baker and Channing J. Der are in the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA.
Channing J. Der: Nicole M. Baker and Channing J. Der are in the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA.

Nature, 2013, vol. 497, issue 7451, 577-578

Abstract: Scientists have long aimed to develop drugs against the cancer-associated protein KRAS, but without success. An approach that targets the oncoprotein's cellular localization reignites lost enthusiasm. See Letter p.638

Date: 2013
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DOI: 10.1038/nature12248

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