Gut metagenome in European women with normal, impaired and diabetic glucose control

Fredrik H. Karlsson, Valentina Tremaroli, Intawat Nookaew, Göran Bergström, Carl Johan Behre, Björn Fagerberg, Jens Nielsen () and Fredrik Bäckhed ()
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Fredrik H. Karlsson: Chalmers University of Technology, SE-412 96 Gothenburg, Sweden
Valentina Tremaroli: The Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden
Intawat Nookaew: Chalmers University of Technology, SE-412 96 Gothenburg, Sweden
Göran Bergström: The Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden
Carl Johan Behre: The Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden
Björn Fagerberg: The Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden
Jens Nielsen: Chalmers University of Technology, SE-412 96 Gothenburg, Sweden
Fredrik Bäckhed: The Wallenberg Laboratory and Sahlgrenska Center for Cardiovascular and Metabolic Research, Institute of Medicine, University of Gothenburg, SE-413 45 Gothenburg, Sweden

Nature, 2013, vol. 498, issue 7452, 99-103

Abstract: The faecal metagenome of a cohort of 145 European women with normal, impaired or diabetic glucose control was characterized and discriminant metagenomic markers for type 2 diabetes were identified; the discriminant markers differed from those of a recent Chinese cohort, suggesting that metagenomic predictive tools may need to be specific for age and geographic location.

Date: 2013
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DOI: 10.1038/nature12198

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