Integration triggers death

Anna Marie Skalka ()
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Anna Marie Skalka: Anna Marie Skalka is at the Fox Chase Cancer Centre, Philadelphia, Pennsylvania 19111, USA.

Nature, 2013, vol. 498, issue 7454, 305-306

Abstract: That HIV cripples the immune system by killing CD4+ T cells has long been known. It now emerges that the protein DNA-PK, activated by viral integration into the host-cell genome, is the agent of this death response. See Letter p.376

Date: 2013
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DOI: 10.1038/nature12254

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