From big data to mechanism

Vivek Swarup and Daniel H. Geschwind ()
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Vivek Swarup: University of California Los Angeles, Los Angeles, California 90095-1761, USA.
Daniel H. Geschwind: David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California 90095-1761, USA.

Nature, 2013, vol. 500, issue 7460, 34-35

Abstract: The gene variant APOE4 is the most common genetic risk factor associated with late-onset Alzheimer's disease. A comprehensive, multilayer study reveals the molecular and cellular signatures of APOE4 in humans. See Article p.45

Date: 2013
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DOI: 10.1038/nature12457

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