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Metabolite turns master regulator

Joshua D. Rabinowitz () and Thomas J. Silhavy
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Joshua D. Rabinowitz: Princeton University, Princeton, New Jersey 08544, USA.
Thomas J. Silhavy: Princeton University, Princeton, New Jersey 08544, USA.

Nature, 2013, vol. 500, issue 7462, 283-284

Abstract: The phenomenon of catabolite repression enables microorganisms to use their favourite carbon source first. New work reveals α-ketoacids as key effectors of this process, with their levels regulating gene expression. See Article p.301

Date: 2013
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DOI: 10.1038/nature12544

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