Avoiding chromosome pathology when replication forks collide

Christian J. Rudolph (), Amy L. Upton, Anna Stockum, Conrad A. Nieduszynski and Robert G. Lloyd
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Christian J. Rudolph: Centre for Genetics and Genomics, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Amy L. Upton: Centre for Genetics and Genomics, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Anna Stockum: Centre for Genetics and Genomics, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Conrad A. Nieduszynski: Centre for Genetics and Genomics, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK
Robert G. Lloyd: Centre for Genetics and Genomics, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK

Nature, 2013, vol. 500, issue 7464, 608-611

Abstract: The site of collision between two chromosome replication forks can be used to reinitiate replication independent of an active origin, with potentially pathogenic effects.

Date: 2013
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DOI: 10.1038/nature12312

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