Mitotic trigger waves and the spatial coordination of the Xenopus cell cycle

Jeremy B. Chang () and James E. Ferrell ()
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Jeremy B. Chang: Stanford University School of Medicine
James E. Ferrell: Stanford University School of Medicine

Nature, 2013, vol. 500, issue 7464, 603-607

Abstract: In an in vitro Xenopus extract system that can undergo cell cycles, mitosis spreads through the cytoplasm in ‘trigger waves’ of Cdk1 activation, which may reflect a more general biological mechanism related to action potentials and calcium waves.

Date: 2013
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DOI: 10.1038/nature12321

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