A gustatory receptor paralogue controls rapid warmth avoidance in Drosophila

Lina Ni, Peter Bronk, Elaine C. Chang, April M. Lowell, Juliette O. Flam, Vincent C. Panzano, Douglas L. Theobald, Leslie C. Griffith and Paul A. Garrity ()
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Lina Ni: National Center for Behavioral Genomics, Brandeis University
Peter Bronk: National Center for Behavioral Genomics, Brandeis University
Elaine C. Chang: National Center for Behavioral Genomics, Brandeis University
April M. Lowell: National Center for Behavioral Genomics, Brandeis University
Juliette O. Flam: National Center for Behavioral Genomics, Brandeis University
Vincent C. Panzano: National Center for Behavioral Genomics, Brandeis University
Douglas L. Theobald: Brandeis University
Leslie C. Griffith: National Center for Behavioral Genomics, Brandeis University
Paul A. Garrity: National Center for Behavioral Genomics, Brandeis University

Nature, 2013, vol. 500, issue 7464, 580-584

Abstract: After previously discovering that the ion channel TRPA1 is used as an internal temperature sensor in Drosophila to control the slow response of flies to shallow thermal gradients, the authors show here that the rapid response of flies to steep warming gradients relies on a different protein, GR28B, providing the first example of a thermosensory role for a gustatory receptor.

Date: 2013
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DOI: 10.1038/nature12390

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