A long genetic explanation

Robert N. Plasschaert and Marisa S. Bartolomei ()
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Robert N. Plasschaert: University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Marisa S. Bartolomei: University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Nature, 2013, vol. 501, issue 7465, 36-37

Abstract: Topoisomerase enzymes facilitate gene transcription by resolving DNA tangles. Malfunction of these enzymes seems to compromise the expression of very long genes, potentially mediating neurodevelopmental disorders. See Article p.58

Date: 2013
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DOI: 10.1038/nature12553

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