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Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

Kenji Maeda, Kanchan Anand, Antonella Chiapparino, Arun Kumar, Mattia Poletto, Marko Kaksonen and Anne-Claude Gavin ()
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Kenji Maeda: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Kanchan Anand: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Antonella Chiapparino: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Arun Kumar: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Mattia Poletto: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Marko Kaksonen: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany
Anne-Claude Gavin: European Molecular Biology Laboratory, EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany

Nature, 2013, vol. 501, issue 7466, 257-261

Abstract: The lipid-binding profiles of all lipid-transfer proteins in Saccharomyces cerevisiae are determined and a new subfamily of oxysterol-binding proteins that function in phosphatidylserine homeostasis and transport is identified.

Date: 2013
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DOI: 10.1038/nature12430

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