Lipopolysaccharide sensing on the inside

Vijay A. K. Rathinam and Katherine A. Fitzgerald ()
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Vijay A. K. Rathinam: University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Katherine A. Fitzgerald: University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

Nature, 2013, vol. 501, issue 7466, 173-175

Abstract: Host-cell detection of lipopolysaccharide in the outer membrane of Gram-negative bacteria was thought to be restricted to the cell-surface receptor TLR4. It emerges that lipopolysaccharide can also be sensed in the cytoplasm.

Date: 2013
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DOI: 10.1038/nature12556

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