Down's syndrome link to ageing

George P. Souroullas and Norman E. Sharpless ()
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George P. Souroullas: Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7295, USA.
Norman E. Sharpless: Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7295, USA.

Nature, 2013, vol. 501, issue 7467, 325-326

Abstract: Triplication of the enzyme USP16 in models of Down's syndrome creates defects in the stem cells resident in adult tissues. This finding provides insight into stem-cell homeostasis during ageing. See Article p.380

Date: 2013
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DOI: 10.1038/nature12558

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