Type 2 innate lymphoid cells control eosinophil homeostasis

Jesse C. Nussbaum, Steven J. Van Dyken, Jakob von Moltke, Laurence E. Cheng, Alexander Mohapatra, Ari B. Molofsky, Emily E. Thornton, Matthew F. Krummel, Ajay Chawla, Hong-Erh Liang and Richard M. Locksley ()
Additional contact information
Jesse C. Nussbaum: University of California San Francisco
Steven J. Van Dyken: University of California San Francisco
Jakob von Moltke: University of California San Francisco
Laurence E. Cheng: University of California San Francisco
Alexander Mohapatra: University of California San Francisco
Ari B. Molofsky: University of California San Francisco
Emily E. Thornton: University of California San Francisco
Matthew F. Krummel: University of California San Francisco
Ajay Chawla: University of California San Francisco
Hong-Erh Liang: University of California San Francisco
Richard M. Locksley: University of California San Francisco

Nature, 2013, vol. 502, issue 7470, 245-248

Abstract: Eosinophil recruitment to the lung and intestine is regulated by type-2-innate-lymphoid-cell-derived IL-5 and IL-13; IL-5 is shown to be induced by the neuropeptide vasoactive intestinal peptide, which is known to coordinate pancreatic secretion with smooth muscle relaxation in response to feeding.

Date: 2013
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DOI: 10.1038/nature12526

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