A juvenile mouse pheromone inhibits sexual behaviour through the vomeronasal system

David M. Ferrero, Lisa M. Moeller, Takuya Osakada, Nao Horio, Qian Li, Dheeraj S. Roy, Annika Cichy, Marc Spehr, Kazushige Touhara and Stephen D. Liberles ()
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David M. Ferrero: Harvard Medical School
Lisa M. Moeller: Institute for Biology II, RWTH Aachen University
Takuya Osakada: Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan
Nao Horio: Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan
Qian Li: Harvard Medical School
Dheeraj S. Roy: Harvard Medical School
Annika Cichy: Institute for Biology II, RWTH Aachen University
Marc Spehr: Institute for Biology II, RWTH Aachen University
Kazushige Touhara: Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan
Stephen D. Liberles: Harvard Medical School

Nature, 2013, vol. 502, issue 7471, 368-371

Abstract: ESP22, a new pheromone produced by juvenile mice before puberty and released through the tears, activates neurons in the vomeronasal organ and inhibits mating behaviour in adult males towards animals expressing this signal.

Date: 2013
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DOI: 10.1038/nature12579

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