Killing from the inside
Paul Saftig () and
Konrad Sandhoff
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Paul Saftig: Paul Saftig is at the Biochemisches Institut, Christian Albrechts-Universität Kiel, 24118 Kiel, Germany.
Konrad Sandhoff: Konrad Sandhoff is at the Life and Medical Sciences Institute, Universität Bonn, 53121 Bonn, Germany.
Nature, 2013, vol. 502, issue 7471, 312-313
Abstract:
Lysosomes are the main degradative compartment in cells, but they are also involved in cell-death pathways. Studies using existing drugs show that lysosomes are excellent pharmacological targets for selectively destroying cancer cells.
Date: 2013
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DOI: 10.1038/nature12692
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