MX2 is an interferon-induced inhibitor of HIV-1 infection

Melissa Kane, Shalini S. Yadav, Julia Bitzegeio, Sebla B. Kutluay, Trinity Zang, Sam J. Wilson, John W. Schoggins, Charles M. Rice, Masahiro Yamashita, Theodora Hatziioannou and Paul D. Bieniasz ()
Additional contact information
Melissa Kane: Aaron Diamond AIDS Research Center
Shalini S. Yadav: Aaron Diamond AIDS Research Center
Julia Bitzegeio: Aaron Diamond AIDS Research Center
Sebla B. Kutluay: Aaron Diamond AIDS Research Center
Trinity Zang: Aaron Diamond AIDS Research Center
Sam J. Wilson: Aaron Diamond AIDS Research Center
John W. Schoggins: Center for the Study of Hepatitis C, The Rockefeller University
Charles M. Rice: Center for the Study of Hepatitis C, The Rockefeller University
Masahiro Yamashita: Aaron Diamond AIDS Research Center
Theodora Hatziioannou: Aaron Diamond AIDS Research Center
Paul D. Bieniasz: Aaron Diamond AIDS Research Center

Nature, 2013, vol. 502, issue 7472, 563-566

Abstract: MX2 is shown to be an interferon-induced inhibitor of HIV-1 infection, and this antiviral activity may involve the inhibition of nuclear import of subviral complexes.

Date: 2013
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DOI: 10.1038/nature12653

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