Synthetic non-oxidative glycolysis enables complete carbon conservation

Igor W. Bogorad, Tzu-Shyang Lin and James C. Liao ()
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Igor W. Bogorad: University of California, Los Angeles, 420 Westwood Plaza, Los Angeles, California 90095, USA.
Tzu-Shyang Lin: University of California, Los Angeles, 420 Westwood Plaza, Los Angeles, California 90095, USA.
James C. Liao: University of California, Los Angeles, 420 Westwood Plaza, Los Angeles, California 90095, USA.

Nature, 2013, vol. 502, issue 7473, 693-697

Abstract: A non-oxidative, cyclic pathway—termed non-oxidative glycolysis—is designed and constructed that enables complete carbon conservation in sugar catabolism to acetyl-coenzyme A, and can be used to achieve a 100% carbon yield to fuels and chemicals.

Date: 2013
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DOI: 10.1038/nature12575

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