EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

Haruya Ohno, Kosaku Shinoda, Kana Ohyama, Louis Z. Sharp and Shingo Kajimura ()
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Haruya Ohno: UCSF Diabetes Center, University of California, San Francisco, 35 Medical Center Way
Kosaku Shinoda: UCSF Diabetes Center, University of California, San Francisco, 35 Medical Center Way
Kana Ohyama: UCSF Diabetes Center, University of California, San Francisco, 35 Medical Center Way
Louis Z. Sharp: UCSF Diabetes Center, University of California, San Francisco, 35 Medical Center Way
Shingo Kajimura: UCSF Diabetes Center, University of California, San Francisco, 35 Medical Center Way

Nature, 2013, vol. 504, issue 7478, 163-167

Abstract: Brown adipose tissue-enriched lysine methyltransferase EHMT1 is an essential enzyme in the PRDM16–C/EBP-β transcriptional complex that controls brown adipose cell fate and energy metabolism.

Date: 2013
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DOI: 10.1038/nature12652

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