The protein quality control system manages plant defence compound synthesis
Jacob Pollier,
Tessa Moses,
Miguel González-Guzmán,
Nathan De Geyter,
Saskia Lippens,
Robin Vanden Bossche,
Peter Marhavý,
Anna Kremer,
Kris Morreel,
Christopher J. Guérin,
Aldo Tava,
Wieslaw Oleszek,
Johan M. Thevelein,
Narciso Campos,
Sofie Goormachtig and
Alain Goossens ()
Additional contact information
Jacob Pollier: VIB, Technologiepark 927, Gent B-9052, Belgium
Tessa Moses: VIB, Technologiepark 927, Gent B-9052, Belgium
Miguel González-Guzmán: VIB, Technologiepark 927, Gent B-9052, Belgium
Nathan De Geyter: VIB, Technologiepark 927, Gent B-9052, Belgium
Saskia Lippens: VIB Bio Imaging Core Gent, VIB, Technologiepark 927, Gent B-9052, Belgium
Robin Vanden Bossche: VIB, Technologiepark 927, Gent B-9052, Belgium
Peter Marhavý: VIB, Technologiepark 927, Gent B-9052, Belgium
Anna Kremer: VIB Bio Imaging Core Gent, VIB, Technologiepark 927, Gent B-9052, Belgium
Kris Morreel: VIB, Technologiepark 927, Gent B-9052, Belgium
Christopher J. Guérin: VIB Bio Imaging Core Gent, VIB, Technologiepark 927, Gent B-9052, Belgium
Aldo Tava: Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Centro di Ricerca per le Produzioni Foraggere e Lattiero Casearie, viale Piacenza 29, Lodi 26900, Italy
Wieslaw Oleszek: Institute of Soil Science and Plant Cultivation - State Research Institute, ul. Czartoryskich 8, Pulawy 24-100, Poland
Johan M. Thevelein: Laboratory of Molecular Cell Biology, Institute of Botany and Microbiology, KU Leuven, Kasteelpark Arenberg 31, Leuven-Heverlee B-3001, Belgium
Narciso Campos: Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avda Diagonal 643, Barcelona 08028, Spain
Sofie Goormachtig: VIB, Technologiepark 927, Gent B-9052, Belgium
Alain Goossens: VIB, Technologiepark 927, Gent B-9052, Belgium
Nature, 2013, vol. 504, issue 7478, 148-152
Abstract:
Plants defend themselves against attackers by producing bioactive secondary metabolites such as triterpene saponins; here, the endoplasmic-reticulum-associated degradation (ERAD) system is shown to control the activity of HMGR, the rate-limiting enzyme in the supply of the terpene precursor isopentenyl diphosphate, thereby preventing unrestrained saponin production and ensuring the integrity of plant development.
Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:504:y:2013:i:7478:d:10.1038_nature12685
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DOI: 10.1038/nature12685
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