Chromatin connectivity maps reveal dynamic promoter–enhancer long-range associations

Yubo Zhang, Chee-Hong Wong, Ramon Y. Birnbaum, Guoliang Li, Rebecca Favaro, Chew Yee Ngan, Joanne Lim, Eunice Tai, Huay Mei Poh, Eleanor Wong, Fabianus Hendriyan Mulawadi, Wing-Kin Sung, Silvia Nicolis, Nadav Ahituv, Yijun Ruan and Chia-Lin Wei ()
Additional contact information
Yubo Zhang: Sequencing Technology Group, Joint Genome Institute, Lawrence Berkeley National Laboratory, Walnut Creek, California 94598, USA
Chee-Hong Wong: Sequencing Technology Group, Joint Genome Institute, Lawrence Berkeley National Laboratory, Walnut Creek, California 94598, USA
Ramon Y. Birnbaum: Institute for Human Genetics, UCSF, San Francisco, California 94158, USA
Guoliang Li: The Jackson Laboratory for Genomic Medicine, University of Connecticut
Rebecca Favaro: University of Milano-Bicocca, 20126 Milano, Italy
Chew Yee Ngan: Sequencing Technology Group, Joint Genome Institute, Lawrence Berkeley National Laboratory, Walnut Creek, California 94598, USA
Joanne Lim: Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
Eunice Tai: Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
Huay Mei Poh: Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
Eleanor Wong: Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
Fabianus Hendriyan Mulawadi: Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
Wing-Kin Sung: Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
Silvia Nicolis: University of Milano-Bicocca, 20126 Milano, Italy
Nadav Ahituv: Institute for Human Genetics, UCSF, San Francisco, California 94158, USA
Yijun Ruan: The Jackson Laboratory for Genomic Medicine, University of Connecticut
Chia-Lin Wei: Sequencing Technology Group, Joint Genome Institute, Lawrence Berkeley National Laboratory, Walnut Creek, California 94598, USA

Nature, 2013, vol. 504, issue 7479, 306-310

Abstract: A chromatin interaction analysis with paired-end tagging (ChIA-PET) approach is used to delineate chromatin interactions mediated by RNA polymerase II in several different stem-cell populations; putative long-range promoter–enhancer interactions are inferred, indicating that linear juxtaposition does not necessarily guide enhancer target selection and prevalent cell-specific enhancer usage.

Date: 2013
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature12716 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:504:y:2013:i:7479:d:10.1038_nature12716

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature12716

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().