A suppression switch

Hanna Starobinets and Jayanta Debnath ()
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Hanna Starobinets: University of California, San Francisco, San Francisco 94143, USA.
Jayanta Debnath: University of California, San Francisco, San Francisco 94143, USA.

Nature, 2013, vol. 504, issue 7479, 225-226

Abstract: The status of the protein p53 determines whether inhibiting the cellular autophagy pathway promotes or inhibits pancreatic cancer in mice. This finding serves as a cautionary tale for clinical trials of autophagy inhibitors. See Letter p.296

Date: 2013
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DOI: 10.1038/nature12841

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