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Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

Kristin Westphalen, Galina A. Gusarova, Mohammad N. Islam, Manikandan Subramanian, Taylor S. Cohen, Alice S. Prince and Jahar Bhattacharya ()
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Kristin Westphalen: Lung Biology Laboratory, Allergy and Critical Care, Columbia University Medical Center
Galina A. Gusarova: Lung Biology Laboratory, Allergy and Critical Care, Columbia University Medical Center
Mohammad N. Islam: Lung Biology Laboratory, Allergy and Critical Care, Columbia University Medical Center
Manikandan Subramanian: Columbia University Medical Center
Taylor S. Cohen: Columbia University Medical Center
Alice S. Prince: Columbia University Medical Center
Jahar Bhattacharya: Lung Biology Laboratory, Allergy and Critical Care, Columbia University Medical Center

Nature, 2014, vol. 506, issue 7489, 503-506

Abstract: Tissue-resident macrophages are shown to stop lipopolysaccharide-induced inflammation by spreading an anti-inflammatory calcium signal to alveolar epithelial cells through connexin-43-positive gap junction channels.

Date: 2014
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DOI: 10.1038/nature12902

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