Conformation-induced remote meta-C–H activation of amines

Ri-Yuan Tang, Gang Li and Jin-Quan Yu ()
Additional contact information
Ri-Yuan Tang: The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
Gang Li: The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA
Jin-Quan Yu: The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA

Nature, 2014, vol. 507, issue 7491, 215-220

Abstract: In anilines and benzylic amines, a recyclable chemical template can direct the olefination and acetoxylation of meta-C–H bonds as far as 11 bonds away from a functional group; in particular, it is able to direct the meta-selective C–H functionalization of bicyclic heterocycles via a highly strained, tricyclic-cyclophane-like palladated intermediate.

Date: 2014
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature12963 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:507:y:2014:i:7491:d:10.1038_nature12963

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature12963

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().