Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

Joseph D. Mancias, Xiaoxu Wang, Steven P. Gygi, J. Wade Harper () and Alec C. Kimmelman ()
Additional contact information
Joseph D. Mancias: Dana-Farber Cancer Institute
Xiaoxu Wang: Dana-Farber Cancer Institute
Steven P. Gygi: Harvard Medical School
J. Wade Harper: Harvard Medical School
Alec C. Kimmelman: Dana-Farber Cancer Institute

Nature, 2014, vol. 509, issue 7498, 105-109

Abstract: Through a quantitative proteomics analysis, a cohort of proteins is identified that associate with autophagosomes, among them a new cargo receptor called NCOA4 that, in response to iron deprivation, targets ferritin to autophagosomes and thereby releases iron.

Date: 2014
References: Add references at CitEc
Citations: View citations in EconPapers (7)

Downloads: (external link)
https://www.nature.com/articles/nature13148 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:509:y:2014:i:7498:d:10.1038_nature13148

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature13148

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().