Identification of genomic alterations in oesophageal squamous cell cancer

Yongmei Song, Lin Li, Yunwei Ou, Zhibo Gao, Enmin Li, Xiangchun Li, Weimin Zhang, Jiaqian Wang, Liyan Xu, Yong Zhou, Xiaojuan Ma, Lingyan Liu, Zitong Zhao, Xuanlin Huang, Jing Fan, Lijia Dong, Gang Chen, Liying Ma, Jie Yang, Longyun Chen, Minghui He, Miao Li, Xuehan Zhuang, Kai Huang, Kunlong Qiu, Guangliang Yin, Guangwu Guo, Qiang Feng, Peishan Chen, Zhiyong Wu, Jianyi Wu, Ling Ma, Jinyang Zhao, Longhai Luo, Ming Fu, Bainan Xu, Bo Chen, Yingrui Li, Tong Tong, Mingrong Wang, Zhihua Liu, Dongxin Lin, Xiuqing Zhang, Huanming Yang, Jun Wang and Qimin Zhan ()
Additional contact information
Yongmei Song: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lin Li: BGI-Shenzhen
Yunwei Ou: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Zhibo Gao: BGI-Shenzhen
Enmin Li: The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, China
Xiangchun Li: BGI-Shenzhen
Weimin Zhang: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Jiaqian Wang: BGI-Shenzhen
Liyan Xu: Institute of Oncologic Pathology, Shantou University Medical College, Shantou 515041, Guangdong, China
Yong Zhou: BGI-Shenzhen
Xiaojuan Ma: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lingyan Liu: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Zitong Zhao: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Xuanlin Huang: BGI-Shenzhen
Jing Fan: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Lijia Dong: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Gang Chen: BGI-Shenzhen
Liying Ma: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Jie Yang: BGI-Shenzhen
Longyun Chen: BGI-Shenzhen
Minghui He: BGI-Shenzhen
Miao Li: BGI-Shenzhen
Xuehan Zhuang: BGI-Shenzhen
Kai Huang: BGI-Shenzhen
Kunlong Qiu: BGI-Shenzhen
Guangliang Yin: BGI-Shenzhen
Guangwu Guo: BGI-Shenzhen
Qiang Feng: BGI-Shenzhen
Peishan Chen: BGI-Shenzhen
Zhiyong Wu: Shantou Central Hospital, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou 515041, Guangdong, China
Jianyi Wu: The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou 515041, Guangdong, China
Ling Ma: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Jinyang Zhao: BGI-Shenzhen
Longhai Luo: BGI-Shenzhen
Ming Fu: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Bainan Xu: Chinese PLA General Hospital, Beijing 100853, China
Bo Chen: Institute of Oncologic Pathology, Shantou University Medical College, Shantou 515041, Guangdong, China
Yingrui Li: BGI-Shenzhen
Tong Tong: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Mingrong Wang: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Zhihua Liu: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Dongxin Lin: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Xiuqing Zhang: BGI-Shenzhen
Huanming Yang: BGI-Shenzhen
Jun Wang: BGI-Shenzhen
Qimin Zhan: State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Nature, 2014, vol. 509, issue 7498, 91-95

Abstract: Using whole-genome and whole-exome sequencing, this study identifies eight significantly mutated genes in oesophageal squamous cell cancer, including two genes, ADAM29 and FAM135B, not previously associated with this cancer type.

Date: 2014
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DOI: 10.1038/nature13176

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