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Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread

Mark A. Czuczman, Ramzi Fattouh, Jorik M. van Rijn, Veronica Canadien, Suzanne Osborne, Aleixo M. Muise, Vijay K. Kuchroo, Darren E. Higgins and John H. Brumell ()
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Mark A. Czuczman: Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G0A4, Canada
Ramzi Fattouh: Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G0A4, Canada
Jorik M. van Rijn: University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands
Veronica Canadien: Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G0A4, Canada
Suzanne Osborne: Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G0A4, Canada
Aleixo M. Muise: Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G0A4, Canada
Vijay K. Kuchroo: Center for Neurologic Diseases, Brigham and Women’s Hospital, Harvard Medical School
Darren E. Higgins: Harvard Medical School
John H. Brumell: Cell Biology Program, Hospital for Sick Children, Toronto, Ontario M5G0A4, Canada

Nature, 2014, vol. 509, issue 7499, 230-234

Abstract: The intracellular bacterial pathogen Listeria monocytogenes is shown to exploit efferocytosis—the process by which dead or dying cells are removed by phagocytosis—to promote cell-to-cell spread during infection.

Date: 2014
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DOI: 10.1038/nature13168

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