Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

Barbara Treutlein, Doug G. Brownfield, Angela R. Wu, Norma F. Neff, Gary L. Mantalas, F. Hernan Espinoza, Tushar J. Desai (), Mark A. Krasnow () and Stephen R. Quake ()
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Barbara Treutlein: Stanford University School of Medicine and Howard Hughes Medical Institute
Doug G. Brownfield: Stanford University School of Medicine and Howard Hughes Medical Institute
Angela R. Wu: Stanford University School of Medicine and Howard Hughes Medical Institute
Norma F. Neff: Stanford University School of Medicine and Howard Hughes Medical Institute
Gary L. Mantalas: Stanford University School of Medicine and Howard Hughes Medical Institute
F. Hernan Espinoza: Stanford University School of Medicine and Howard Hughes Medical Institute
Tushar J. Desai: Stanford University School of Medicine
Mark A. Krasnow: Stanford University School of Medicine and Howard Hughes Medical Institute
Stephen R. Quake: Stanford University School of Medicine and Howard Hughes Medical Institute

Nature, 2014, vol. 509, issue 7500, 371-375

Abstract: Single-cell transcriptome analysis enables the direct measurement of cell types and lineage hierarchies of the developing distal lung epithelium and identifies a population of bipotential alveolar progenitor cells.

Date: 2014
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DOI: 10.1038/nature13173

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