Clonal selection in the germinal centre by regulated proliferation and hypermutation

Alexander D. Gitlin, Ziv Shulman and Michel C. Nussenzweig ()
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Alexander D. Gitlin: Laboratory of Molecular Immunology, The Rockefeller University
Ziv Shulman: Laboratory of Molecular Immunology, The Rockefeller University
Michel C. Nussenzweig: Laboratory of Molecular Immunology, The Rockefeller University

Nature, 2014, vol. 509, issue 7502, 637-640

Abstract: Clonal expansion and hypermutation of B cells in the germinal centre are regulated by the amount of antigen that the B cells present to follicular helper T cells.

Date: 2014
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DOI: 10.1038/nature13300

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