Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

James J. H. Chong, Xiulan Yang, Creighton W. Don, Elina Minami, Yen-Wen Liu, Jill J. Weyers, William M. Mahoney, Benjamin Van Biber, Savannah M. Cook, Nathan J. Palpant, Jay A. Gantz, James A. Fugate, Veronica Muskheli, G. Michael Gough, Keith W. Vogel, Cliff A. Astley, Charlotte E. Hotchkiss, Audrey Baldessari, Lil Pabon, Hans Reinecke, Edward A. Gill, Veronica Nelson, Hans-Peter Kiem, Michael A. Laflamme and Charles E. Murry ()
Additional contact information
James J. H. Chong: Center for Cardiovascular Biology, University of Washington
Xiulan Yang: Center for Cardiovascular Biology, University of Washington
Creighton W. Don: University of Washington
Elina Minami: Center for Cardiovascular Biology, University of Washington
Yen-Wen Liu: Center for Cardiovascular Biology, University of Washington
Jill J. Weyers: Center for Cardiovascular Biology, University of Washington
William M. Mahoney: Center for Cardiovascular Biology, University of Washington
Benjamin Van Biber: Center for Cardiovascular Biology, University of Washington
Savannah M. Cook: Institute for Stem Cell and Regenerative Medicine, University of Washington
Nathan J. Palpant: Center for Cardiovascular Biology, University of Washington
Jay A. Gantz: Center for Cardiovascular Biology, University of Washington
James A. Fugate: Center for Cardiovascular Biology, University of Washington
Veronica Muskheli: Center for Cardiovascular Biology, University of Washington
G. Michael Gough: Washington National Primate Research Center, University of Washington
Keith W. Vogel: Washington National Primate Research Center, University of Washington
Cliff A. Astley: Washington National Primate Research Center, University of Washington
Charlotte E. Hotchkiss: Washington National Primate Research Center, University of Washington
Audrey Baldessari: Washington National Primate Research Center, University of Washington
Lil Pabon: Center for Cardiovascular Biology, University of Washington
Hans Reinecke: Center for Cardiovascular Biology, University of Washington
Edward A. Gill: University of Washington
Veronica Nelson: Fred Hutchinson Cancer Research Center
Hans-Peter Kiem: University of Washington
Michael A. Laflamme: Center for Cardiovascular Biology, University of Washington
Charles E. Murry: Center for Cardiovascular Biology, University of Washington

Nature, 2014, vol. 510, issue 7504, 273-277

Abstract: Regeneration of the heart muscle after myocardial infarction with cardiomyocytes derived from human embryonic stem cells is demonstrated in non-human primates, with the grafts showing evidence of electromechanical coupling, although they were also associated with non-fatal arrhythmias.

Date: 2014
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.nature.com/articles/nature13233 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:510:y:2014:i:7504:d:10.1038_nature13233

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature13233

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().