Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

Curtis M. Schauder, Xudong Wu, Yasunori Saheki, Pradeep Narayanaswamy, Federico Torta, Markus R. Wenk, Pietro De Camilli () and Karin M. Reinisch ()
Additional contact information
Curtis M. Schauder: Yale School of Medicine
Xudong Wu: Yale School of Medicine
Yasunori Saheki: Yale School of Medicine
Pradeep Narayanaswamy: National University of Singapore, 117543 Singapore
Federico Torta: Yong Loo Lin School of Medicine, National University of Singapore, 117599 Singapore
Markus R. Wenk: Yong Loo Lin School of Medicine, National University of Singapore, 117599 Singapore
Pietro De Camilli: Yale School of Medicine
Karin M. Reinisch: Yale School of Medicine

Nature, 2014, vol. 510, issue 7506, 552-555

Abstract: Several proteins localized at membrane contact sites contain an SMP domain, which has been proposed to act as a lipid-binding module; here, the crystal structure of a fragment of the extended synaptotagmin 2 protein, including its SMP, is presented, and indicates that this protein may have a direct role in lipid transport.

Date: 2014
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature13269 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:510:y:2014:i:7506:d:10.1038_nature13269

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature13269

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().