Purkinje-cell plasticity and cerebellar motor learning are graded by complex-spike duration

Yan Yang () and Stephen G. Lisberger ()
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Yan Yang: Duke University
Stephen G. Lisberger: Duke University

Nature, 2014, vol. 510, issue 7506, 529-532

Abstract: Recordings from monkeys during motor learning suggest that durations of complex-spike (CS) responses to climbing-fibre inputs are meaningful signals correlated across the Purkinje-cell population during motor learning; longer climbing-fibre bursts lead to longer-duration CS responses, larger synaptic depression and stronger learning, thus forming a graded instruction.

Date: 2014
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DOI: 10.1038/nature13282

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