BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks

Nicholas A. Willis, Gurushankar Chandramouly, Bin Huang, Amy Kwok, Cindy Follonier, Chuxia Deng and Ralph Scully ()
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Nicholas A. Willis: Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue
Gurushankar Chandramouly: Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue
Bin Huang: Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue
Amy Kwok: Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue
Cindy Follonier: Princeton University, 101 Lewis Thomas Laboratory, Washington Road, Princeton, New Jersey 08544, USA
Chuxia Deng: NIDDK, National Institutes of Health, Building 10, Room 9N105, 10 Center Drive
Ralph Scully: Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue

Nature, 2014, vol. 510, issue 7506, 556-559

Abstract: Direct evidence for the role of BRCA1 in controlling homologous recombination at stalled replication forks has been obtained in mammalian cells using the bacterial Tus/Ter system.

Date: 2014
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DOI: 10.1038/nature13295

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