Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

Lieselotte Vande Walle, Nina Van Opdenbosch, Peggy Jacques, Amelie Fossoul, Eveline Verheugen, Peter Vogel, Rudi Beyaert, Dirk Elewaut, Thirumala-Devi Kanneganti, Geert van Loo and Mohamed Lamkanfi ()
Additional contact information
Lieselotte Vande Walle: VIB, Ghent B-9000, Belgium
Nina Van Opdenbosch: VIB, Ghent B-9000, Belgium
Peggy Jacques: Ghent University, Ghent B-9000, Belgium
Amelie Fossoul: VIB, Ghent B-9000, Belgium
Eveline Verheugen: Ghent University, Ghent B-9000, Belgium
Peter Vogel: St. Jude Children’s Research Hospital
Rudi Beyaert: Inflammation Research Center, VIB, Ghent B-9052, Belgium
Dirk Elewaut: Ghent University, Ghent B-9000, Belgium
Thirumala-Devi Kanneganti: St. Jude Children’s Research Hospital
Geert van Loo: Inflammation Research Center, VIB, Ghent B-9052, Belgium
Mohamed Lamkanfi: VIB, Ghent B-9000, Belgium

Nature, 2014, vol. 512, issue 7512, 69-73

Abstract: Pathogenesis of rheumatoid arthritis depends critically on the NLRP3 inflammasome/interleukin-1 signalling axis.

Date: 2014
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DOI: 10.1038/nature13322

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