Genome-scale functional characterization of Drosophila developmental enhancers in vivo
Evgeny Z. Kvon,
Tomas Kazmar,
Gerald Stampfel,
J. Omar Yáñez-Cuna,
Michaela Pagani,
Katharina Schernhuber,
Barry J. Dickson and
Alexander Stark ()
Additional contact information
Evgeny Z. Kvon: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Tomas Kazmar: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Gerald Stampfel: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
J. Omar Yáñez-Cuna: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Michaela Pagani: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Katharina Schernhuber: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Barry J. Dickson: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Alexander Stark: Research Institute of Molecular Pathology (IMP), Vienna Biocenter VBC, Dr Bohr-Gasse 7, 1030 Vienna, Austria
Nature, 2014, vol. 512, issue 7512, 91-95
Abstract:
Systematically assaying the activity of 7,705 candidate enhancers during Drosophila embryogenesis shows that nearly half are active in the embryo and display dynamic spatial patterns during development; enhancer activity is matched to expression patterns of putative target genes and predictive cis-regulatory motifs are identified.
Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:512:y:2014:i:7512:d:10.1038_nature13395
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DOI: 10.1038/nature13395
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