The Get1/2 transmembrane complex is an endoplasmic-reticulum membrane protein insertase

Fei Wang, Charlene Chan, Nicholas R. Weir and Vladimir Denic ()
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Fei Wang: Harvard University, Northwest Labs, Cambridge, Massachusetts 02138, USA
Charlene Chan: Harvard University, Northwest Labs, Cambridge, Massachusetts 02138, USA
Nicholas R. Weir: Harvard University, Northwest Labs, Cambridge, Massachusetts 02138, USA
Vladimir Denic: Harvard University, Northwest Labs, Cambridge, Massachusetts 02138, USA

Nature, 2014, vol. 512, issue 7515, 441-444

Abstract: The receptor for the cytoplasmic factor that targets tail-anchored proteins to the endoplasmic reticulum is an enzyme that enables a facilitated insertion path into the lipid bilayer.

Date: 2014
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DOI: 10.1038/nature13471

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