Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

Jae Myoung Suh, Johan W. Jonker, Maryam Ahmadian, Regina Goetz, Denise Lackey, Olivia Osborn, Zhifeng Huang, Weilin Liu, Eiji Yoshihara, Theo H. van Dijk, Rick Havinga, Weiwei Fan, Yun-Qiang Yin, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, Jerrold M. Olefsky, Moosa Mohammadi, Michael Downes () and Ronald M. Evans ()
Additional contact information
Jae Myoung Suh: Gene Expression Laboratory, Salk Institute for Biological Studies
Johan W. Jonker: Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Maryam Ahmadian: Gene Expression Laboratory, Salk Institute for Biological Studies
Regina Goetz: New York University School of Medicine
Denise Lackey: University of California at San Diego
Olivia Osborn: University of California at San Diego
Zhifeng Huang: New York University School of Medicine
Weilin Liu: Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Eiji Yoshihara: Gene Expression Laboratory, Salk Institute for Biological Studies
Theo H. van Dijk: Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Rick Havinga: Center for Liver, Digestive and Metabolic Diseases, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
Weiwei Fan: Gene Expression Laboratory, Salk Institute for Biological Studies
Yun-Qiang Yin: Gene Expression Laboratory, Salk Institute for Biological Studies
Ruth T. Yu: Gene Expression Laboratory, Salk Institute for Biological Studies
Christopher Liddle: The Storr Liver Unit, Westmead Millennium Institute and University of Sydney, Westmead Hospital
Annette R. Atkins: Gene Expression Laboratory, Salk Institute for Biological Studies
Jerrold M. Olefsky: University of California at San Diego
Moosa Mohammadi: New York University School of Medicine
Michael Downes: Gene Expression Laboratory, Salk Institute for Biological Studies
Ronald M. Evans: Gene Expression Laboratory, Salk Institute for Biological Studies

Nature, 2014, vol. 513, issue 7518, 436-439

Abstract: Pharmacological fibroblast growth factor 1 (FGF1) normalizes blood glucose in diabetic mice by means of an FGF receptor signalling pathway that is independent of its mitogenic activity.

Date: 2014
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://www.nature.com/articles/nature13540 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:513:y:2014:i:7518:d:10.1038_nature13540

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature13540

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().