Centriole amplification by mother and daughter centrioles differs in multiciliated cells

Adel Al Jord, Anne-Iris Lemaître, Nathalie Delgehyr, Marion Faucourt, Nathalie Spassky () and Alice Meunier ()
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Adel Al Jord: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, F-75005 Paris, France
Anne-Iris Lemaître: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, F-75005 Paris, France
Nathalie Delgehyr: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, F-75005 Paris, France
Marion Faucourt: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, F-75005 Paris, France
Nathalie Spassky: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, F-75005 Paris, France
Alice Meunier: Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, F-75005 Paris, France

Nature, 2014, vol. 516, issue 7529, 104-107

Abstract: Using advanced microscopy techniques, the process of centriole amplification in multiciliated cells is explored, and the daughter centriole identified as the primary nucleation site of more than 90% of the new centrioles, contesting existing de novo theories of centriolar amplification and highlighting a new centrosome asymmetry.

Date: 2014
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DOI: 10.1038/nature13770

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