Resistance through repopulation

Ian F. Tannock ()
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Ian F. Tannock: Princess Margaret Cancer Centre, Toronto, Ontario M5G 2M9, Canada.

Nature, 2015, vol. 517, issue 7533, 152-153

Abstract: Bladder-cancer cells have been found to release prostaglandin E2 when they are killed by chemotherapy. Paradoxically, this molecule stimulates the proliferation of surviving cancer stem cells, leading to tumour repopulation. See Letter p.209

Date: 2015
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DOI: 10.1038/nature14075

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